Avonex free trial

The main measure of the study was the time it took for participants to have an increase in disability of 1 point on the EDSS scale which lasted for at least 6 months. The group taking Avonex were significantly less likely to have this increase in disability.

This study was set up in to evaluate the long-term benefits of beta interferons and Copaxone glatiramer acetate. At the end of the study, changes in disability levels were compared to those recorded from an untreated group. If you are considering treatment with one of the disease modifying drugs for relapsing MS, this book will help you to understand how the drugs work and to have informed discussions with your health team about your treatment options.

Compare the different types of disease modifying drugs DMDs that are available to treat relapsing MS. Find out about people's different experiences of MS drugs and treatments, from DMDs to alternative therapies. Print this page. Skip to content. Skip to navigation. How is MS diagnosed? Guidance for young people with MS Bladder or bowel problems? You're not alone Cabbages and an MS King Call for national neurology plan following largest ever survey of people with neurological conditions Can't take the heat?

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Stem cell transplants in the news Temelimab: early clinical trial suggests potential for remyelination Testing iStep-MS, a new programme to encourage physical activity Treatments for foot drop compared Tysabri risk of PML with extended interval dosing. Common side effects include flu-like symptoms and injection site reactions. What is Avonex used for in MS? Who can take Avonex? Contraindications It's important that you tell your MS team if you have any health problems or are taking other medicines.

Conception and pregnancy The prescribing advice for Avonex during pregnancy and breastfeeding is appropriately cautious.

How do I take Avonex? What side effects could I get with Avonex? Overview Common side effects include: Flu-like symptoms, such as headache, muscle ache and stiffness, chills or fever, following an injection Injection site reactions You are more likely to have these side effects when you first start taking Avonex.

A neurologist or MS nurse may suggest ways to reduce these side effects including: To help with flu-like symptoms, it may be helpful to change the time of day of injection in order to sleep through the worst of the side effects To help reduce fever, paracetamol or ibuprofen can be taken before the injection and at four to six hour intervals after the injection, as required Common side effects affecting more than 1 person in flu-like symptoms headache injection site reactions blood cell abnormalities feeling weak or tired difficulty sleeping diarrhoea, nausea and vomiting muscular or joint pain depression Less common side effects affecting less than 1 person in changes in menstruation periods liver abnormalities allergic reactions heart problems and high blood pressure hair thinning or loss damage to small blood vessels leading to kidney problems A full list of side effects is included in the manufacturer's Patient Information Leaflet.

Assessment before treatment Before starting Avonex, you should have blood tests to measure blood cell counts and check liver function. Assessment during treatment Once you've started treatment, you'll have blood tests to measure blood cell counts and monitor liver function, generally every three months for the first year, then less frequently.

How does Avonex work? Avonex research. FDA Resources. Arms and Interventions. Outcome Measures. These are counts of new or significantly enlarged lesions over 10 years on brain MRI reflecting interval radiographic disease activity. Eligibility Criteria. Information from the National Library of Medicine Choosing to participate in a study is an important personal decision.

Contacts and Locations. Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials. More Information. Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. N Engl J Med. IM interferon beta-1a delays definite multiple sclerosis 5 years after a first demyelinating event.

Epub Jan Association between immediate initiation of intramuscular interferon beta-1a at the time of a clinically isolated syndrome and long-term outcomes: a year follow-up of the Controlled High-Risk Avonex Multiple Sclerosis Prevention Study in Ongoing Neurological Surveillance.

Arch Neurol. Epub Oct Mult Scler. Disease-related determinants of quality of life 10 years after clinically isolated syndrome. Int J MS Care. Keywords provided by R. National Library of Medicine U. National Institutes of Health U. Department of Health and Human Services. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Drug: interferon beta 1a 30 ug IM once weekly. Phase 4. Study Type :. Interventional Clinical Trial. Actual Enrollment :.

Open label study: The outcome committee determined the primary outcome event the development of Clinically definite MS without knowledge of original treatment assignment and the central MRI reading center was not aware of original treatment assignments.